The Molecular Combing technology provides a powerful quality control tool for the optimization of gene editing technologies aimed at therapy and also to validate edited cell lines and animal models.
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> Unbiased assessment of editing events thanks to the direct visualization on single DNA molecules
> Any error larger than 1kb can be detected in the target locus
> Detection of rare events
> Multiplexing up to 5 loci
> The technology also allows the studies of DNA replication, Damage and Repair in a separate assay