The FiberProbes® for BRCA is a set of Genomic Morse Codes (GMC), developed by Genomic Vision, aims to identify and characterize major rearrangements that affect the BRCA1 and BRCA2 genes.
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Structural variations in BRCA genes include not only small alterations, but also complex genome rearrangements that are far more difficult to characterize, even via the most effective technologies.
The Molecular Combing technology associated with the Genomic Morse Code strategy is able to efficiently detect the full spectrum of large rearrangements, including the often problematic tandem repeat duplications that occur in the flanking regions of the BRCA genes. Only a method that visualizes large genomic regions can overcome these constraints.